a clinical randomized trial on endocervical inflammatory cytokines and betamethasone in prime-gravid pregnant women at risk of preterm labor
نویسندگان
چکیده
background: there are strong evidences suggesting the secretion of different cytokines in cervical fluid during preterm labor. betamethasone is widely administered for several reasons in preterm conditions. objective: to investigate the possible effect of betamethasone on endocervical cytokine concentration of women at risk of preterm labor. methods: in a randomized clinical trial of 80 prime-gravid women in preterm labor between 34 and 37 weeks of gestation, cervical fluid was collected. endocervical concentration of inflammatory cytokines were analyzed before and 48 hours after betamethasone treatment for the evaluation of il-8, il-17, ifn-γ and tgf-β. wilcoxon and mann-whitney tests were employed for statistical analysis. χ2 and student’s t tests were used whenever needed. results: all the measured cytokines showed significant changes in the betamethasone treated group. il-17 (p=0.001), il-8 (p=0.001), and ifn- γ (p
منابع مشابه
A Clinical Randomized Trial on Endocervical Inflammatory Cytokines and Betamethasone in Prime-Gravid Pregnant Women at Risk of Preterm Labor
Background: There are strong evidences suggesting the secretion of different cytokines in cervical fluid during preterm labor. Betamethasone is widely administered for several reasons in preterm conditions. Objective: To Investigate the possible effect of betamethasone on endocervical cytokine concentration of women at risk of preterm labor. Methods: In a randomized clinical trial of 80 prime-g...
متن کاملComparison of Risk of Preterm Labor between Vaginal Progesterone and17-Alpha-Hydroxy-Progesterone Caproate in Women with Threatened Abortion: A Randomized Clinical Trial
Objective Threatened miscarriage is a common complication in pregnancy that leads to adverse pregnancy outcomes such as preterm labor. This study aimed to compare the vaginal progesterone (Cyclogest) versus 17-alpha-hydroxyprogesterone caproate (Proluton) on preventing preterm labor in pregnant women with threatened abortion at less than 34 weeks’ gestational age. MaterialsAndMethods This balan...
متن کاملThe effect of enalapril on pro-inflammatory cytokines in patients with migraine: a double-blind, randomized clinical trial
Background: One of the possible mechanisms of migraine pathophysiology is neuro inflammation in which, according to previous studies, some changes happen in inflammatory factors like interleukins, adhesion molecules or acute phase reactants. Cytokines may have an essential role in the neurovascular inflammation and also in the process of pain especially in migraine patients. On the other hand, ...
متن کاملThe Effect of Counseling on Hemoglobin, Hematocrit and Weight Gain in Teenage Pregnant Women: A Randomized Clinical Trial
Background Pregnant women’s health is a major health priority in all countries. Teenage pregnancies can be high-risk. This study was conducted to determine the effect of counseling on hemoglobin, hematocrit and weight gain in teenage pregnant women. Materials and Methods This randomized, controlled, clinical trial was conducted on 120 teenage women with a gestational age of 20 to 24 months pres...
متن کاملeffects of antenatal corticosteroids on maternal serum indicators of infection in women at risk for preterm delivery: a randomized trial comparing betamethasone and dexamethasone
normal 0 false false false en-us x-none ar-sa objective: to compare the effect of betamethasonemethasone (betamethasone) and dexamethasonemethasone (dexamethasone) on maternal white blood cell (wbc) and differential count, erythrocyte sedimentation rate (esr), apgar score, maternal and fetal plasma glucose and length of admission to delivery , gestational age at delivery in women at risk of pre...
متن کاملThe effect of aspirin on preeclampsia and fetal growth restriction (FGR) in obese pregnant women : a randomized controlled clinical trial
Background: To evaluate the effect of aspirin on preeclampsia and fetal growth restriction (FGR) in obese pregnant women. Methods: A randomized clinical trial with 187 participants. Participants were allocated to either an intervention (aspirin; n=89) or control (placebo; n=98) group. In two groups, intervention was done from 13-20 until 34 weeks of pregnancy. Outcomes were preeclampsia and FG...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of immunologyجلد ۹، شماره ۳، صفحات ۱۹۹-۲۰۷
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023